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Can L-Methionine and Vitamin B9 (Folic Acid) be taken at the same time?

Find out if l-methionine and vitamin B9 can be taken at the same time, or if they are best taken separately.

L-methionine with vitamin B9

Short answer: Useful in the same plan

While not found to provide additional benefits when taken at the exact same time, research has shown that l-methionine pairs well with vitamin B9.

Also taken with vitamin B9, for pregnancy and heart health

Vitamin B9 supplies the methyl group that turns homocysteine back into methionine, so the two sit at opposite ends of one reaction.

Also taken with l-methionine, for liver health and glutathione

L-methionine is the usual companion to vitamin B9 when the aim is pregnancy, heart health, liver health and glutathione, and the pair is kept together for exactly that reason.

Also taken with TMG or SAMe, for methylation

The case for taking TMG with vitamin B9 rests on pregnancy, heart health and methylation, which the pair covers between the two of them. SAMe, which also focuses on methylation, offers similar results.

Timing is everything

Many supplements are dependent on being taken at the right time, or with the right meal, for proper absorption. For example, fat-soluble vitamins such as vitamin D should be taken together with a high-fat meal. Stimulating supplements, such as rhodiola or ginseng, should avoid being taken too late in the day.

The perfect match

Some supplements are known to complement each other when taken together, either because one helps the other to be absorbed, or because their effects compliment each other. Well known combos include vitamin D3, vitamin K2 and magnesium, or quercetin and bromelain, but there are many others.

Incompatibilities

Likewise, some supplements can compete for absorption or react negatively if taken together. For example, calcium and magnesium compete for absorption, so they are best taken several hours apart, and fiber-heavy supplements such as psyllium husk should be taken by themselves, separate from all other supplements.

Potential additions

The Vitamin Plan will automatically detect if there is a recurring theme in the supplements that you are taking, and suggest a focused addition or two for that theme. For example, if your plan seems to be mostly centered around joint health, it may suggest adding glucosamine or collagen if you didn’t add them yet.

Remember

A balanced diet and a healthy lifestyle always come first, and supplements are meant to be just that: supplementary. While every effort has been made to ensure that the data on this page is accurate, said accuracy can never be guaranteed. The information provided is not medical advice, it is not intended to cover all possible interactions or adverse effects, and neither is it a substitute for the expertise of professional healthcare practitioners. You are always encouraged to do your own research, and to consult with your trusted doctor or pharmacist before taking any supplements.

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