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Can L-Proline and Vitamin C be taken at the same time?

Find out if l-proline and vitamin C can be taken at the same time, or if they are best taken separately.

L-proline with vitamin C

Short answer: Useful in the same plan

While not found to provide additional benefits when taken at the exact same time, research has shown that l-proline pairs well with vitamin C.

Also taken with L-lysine and vitamin C, for cardiovascular health

L-proline features prominently in Linus Pauling's heart health protocol, alongside l-lysine and vitamin C.

That protocol is based on the idea that l-lysine relates to atherosclerotic plaques that adhere to damaged artery walls, while L-proline sits alongside vitamin C in collagen research around those artery walls.

Also taken with L-lysine and L-proline, for cardiovascular health

The great Linus Pauling promoted an artery-cleaning protocol that involved taking large amounts of l-lysine, l-proline and vitamin C with the idea of supporting collagen in artery walls, and there is research that supports the theory behind the mechanism: l-lysine and l-proline serve to decrease the plaque while vitamin C ensures that the artery walls, or endothelium, remains smooth, as it is believed damaged (rough) artery walls are the principal trigger for plaque to accumulate within them.

Timing is everything

Many supplements are dependent on being taken at the right time, or with the right meal, for proper absorption. For example, fat-soluble vitamins such as vitamin D should be taken together with a high-fat meal. Stimulating supplements, such as rhodiola or ginseng, should avoid being taken too late in the day.

The perfect match

Some supplements are known to complement each other when taken together, either because one helps the other to be absorbed, or because their effects compliment each other. Well known combos include vitamin D3, vitamin K2 and magnesium, or quercetin and bromelain, but there are many others.

Incompatibilities

Likewise, some supplements can compete for absorption or react negatively if taken together. For example, calcium and magnesium compete for absorption, so they are best taken several hours apart, and fiber-heavy supplements such as psyllium husk should be taken by themselves, separate from all other supplements.

Potential additions

The Vitamin Plan will automatically detect if there is a recurring theme in the supplements that you are taking, and suggest a focused addition or two for that theme. For example, if your plan seems to be mostly centered around joint health, it may suggest adding glucosamine or collagen if you didn’t add them yet.

Remember

A balanced diet and a healthy lifestyle always come first, and supplements are meant to be just that: supplementary. While every effort has been made to ensure that the data on this page is accurate, said accuracy can never be guaranteed. The information provided is not medical advice, it is not intended to cover all possible interactions or adverse effects, and neither is it a substitute for the expertise of professional healthcare practitioners. You are always encouraged to do your own research, and to consult with your trusted doctor or pharmacist before taking any supplements.

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