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Chromium

Chromium plays a key role in cardiovascular health, and in the regulation of blood sugar and blood pressure levels in particular.

What is chromium good for?

Short answer: Chromium is studied for blood sugar levels.
Chromium is one of the lesser known but still essential minerals that we require in order to live, as it plays a vital role in blood sugar regulation through the hormone insulin.

Chromium is available in several foods such as fish, shellfish, meat, nuts, grains, certain vegetables, and above all, brewer's yeast. Intakes vary widely, and survey estimates of average intake sit below the amounts used in most chromium studies.

Blood sugar and insulin regulation

Research has looked at chromium supplementation and blood sugar levels in people that have diabetes, a condition in which the body can struggle to produce enough insulin, or to put the insulin it does produce to good use, which results in a buildup of glucose in the bloodstream.

Chromium supplementation is studied for its effect on blood sugar levels in people with diabetes.
Chromium supplementation is studied for its effect on blood sugar levels in people with diabetes.


Chromium is also studied in relation to insulin doses in diabetes.

Role in blood pressure research

Some animal studies have also looked at chromium and blood pressure levels, although this effect in humans is not established.

When should I take chromium?

Short answer: Chromium supplements are best taken with breakfast, lunch, or another early meal.

For maximum absorption, it is generally advised to take chromium with a meal. Also, as it is known to potentially interfere with sleep, chromium is best taken early in the day in order to avoid any disruption to your sleep schedule, such as with breakfast or lunch.

What else pairs well with chromium?

Short answer: While not found to provide additional benefits when taken at the exact same time, research has shown that chromium pairs well with grape seed extract, l-carnosine, magnesium, vitamin B3 and vitamin B7.

Also taken with biotin, for blood sugar

Chromium and biotin, also known as vitamin B7, both play roles in regulating carbohydrate metabolism, and research has looked at a combination of chromium and biotin and blood sugar levels in people with type 2 diabetes.

Also taken with niacin, for blood sugar & cholesterol levels

Chromium has also been studied with niacin, also known as vitamin B3, in relation to the body's absorption of chromium and to blood sugar and cholesterol levels.

Also taken with grape seed extract, for cholesterol levels

Chromium has been tested together with grape seed extract, and one study reported that over the course of a two-month period, combined supplementation of chromium and grape seed extract was associated with much lower LDL cholesterol levels than when the supplements were taken individually.

Also taken with magnesium, for insulin sensitivity

Similar results were reported when chromium was used in the same routine with magnesium, with insulin resistance lower when both were combined, compared to when the supplements were taken separately.

Also taken with L-carnosine & cinnamon, for blood sugar

Also worth mentioning is a study that involved a four-month treatment using a combination of chromium, l-carnosine and cinnamon in people with overweight or obesity who had pre-diabetes.

The study concluded that this combination was associated with better blood sugar levels, inflammatory markers, and overall levels of fat-free mass, and the combination is also studied in pre-diabetes.

What are natural sources of chromium?

Short answer: Natural sources of chromium include brewer's yeast, mussels, beef, chicken, broccoli and green beans.

If you are interested in obtaining your daily chromium through your diet, you can often find it in:

Who should avoid taking chromium?

Short answer: Avoid taking chromium supplements if you have kidney problems or liver problems.

Before taking chromium supplements, check with your trusted healthcare professional if any of the following apply to you:

  • Kidney problems
  • Liver problems

Kidney and liver problems

Chromium is cleared by your kidneys and handled by your liver, so advanced kidney disease or liver disease is the situation where a concentrated chromium supplement is best avoided. The amounts in a multivitamin are a different question from the gram-level chromium picolinate, but either one is still worth mentioning to your doctor if you suffer from any kidney or liver condition.

Remember to always discuss any vitamins or supplements with your trusted healthcare professional if you are suffering from any health conditions.

Possible side effects of chromium

Short answer: Side effects of chromium supplements can include gastrointestinal upset.

Possible side effects from taking chromium supplements may include (but are not limited to) the following:

  • Gastrointestinal upset

Stomach upset is the usual complaint with a chromium capsule.

If you are experiencing negative side effects from taking chromium supplements, stop taking them immediately and reach out to your trusted healthcare professional.

Drug interactions with chromium

Short answer: Chromium supplements can interact with diabetes medicines, levothyroxine and NSAIDs.

The medicines listed below are the ones most often named in interaction reports for chromium, but it is by no means a comprehensive list:

  • Diabetes medicines
  • Levothyroxine
  • NSAIDs

If you are taking any prescription drugs or medication, check with your trusted healthcare professional before taking chromium supplements.

Can I take chromium while pregnant or breastfeeding?

Short answer: Chromium supplements do not have sufficient safety data during pregnancy and breastfeeding.

Chromium needs rise only slightly during pregnancy, to 30 mcg a day, and it appears in blood sugar research because it is part of the insulin-signalling picture. A shortfall is rare, and trials of chromium for gestational diabetes haven't produced a clear benefit. High-dose chromium picolinate has been linked with kidney and liver strain, and it isn't a routine pregnancy supplement.

Remember to always discuss any vitamins or supplements with your trusted healthcare professional while pregnant or breastfeeding, or while attempting to conceive.

What are deficiency symptoms of chromium?

Short answer: Chromium deficiency symptoms can include chromium deficiency is poorly defined in free-living people.

Possible signs of chromium deficiency may include (but are not limited to) the following:

  • Chromium deficiency is poorly defined in free-living people

A chromium tablet is not a diabetes treatment.

If you are experiencing abnormal symptoms, reach out to your trusted healthcare professional as soon as possible.

Where should I store chromium?

Short answer: You can store chromium supplements in the cupboard.

For optimal shelf life, it is recommended to keep chromium supplements stored in the cupboard. Always make sure the bottle or container is tightly closed, and kept away from sources of light, heat and humidity.

Chromium data sources & further reading

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Last updated October 30th, 2026

Remember

A balanced diet and a healthy lifestyle always come first, and supplements are meant to be just that: supplementary. While every effort has been made to ensure that the data on this page is accurate, said accuracy can never be guaranteed. The information provided is not medical advice, it is not intended to cover all possible interactions or adverse effects, and neither is it a substitute for the expertise of professional healthcare practitioners. You are always encouraged to do your own research, and to consult with your trusted doctor or pharmacist before taking any supplements.

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